Get to know our body's organ regeneration cycle - GO.CARE Blog

Get to know our body’s organ regeneration cycle

Author: Jonathan Pham
Review Date: 26/12/2019 | Last Modified: 26/12/2019
Get to know our body’s organ regeneration cycle

Regeneration is the process of regrowing a lost/ damaged cell, tissue or organ from remaining tissues. In adults, certain organs are capable of regenerating. For example, skin cells are constantly being renewed and repaired every day. However, not all body parts come with this ability. Research on the body’s organ regeneration cycle has led to the development of regenerative medicine – which aims to stimulate tissue regeneration and replacement.

An overview of the body’s organ regeneration cycle

Regeneration is a natural reaction that includes a chain of anabolic and catabolic processes. In these processes, cells are destroyed and then reproduced again. The body gets rid of old, damaged cells before replacing them with new stem cells. This process of regeneration is not the same between different organs. For example, skin cells are renewed within 30 days, while red blood cells come with a life cycle of 120 days. For bone cells, the regeneration takes place once every 3 months.

The above-mentioned process of regeneration is critical to the maintenance of life. Every 5 days, the stomach creates a new lining. If this process is interrupted, hydrochloric acid from stomach juice will damage the stomach and cause death.

Over time, the natural aging process affects the body’s organ regeneration cycle, making it slower to recover from damage and more susceptible to diseases.

Organ regeneration cycle

Our body’s organ regeneration cycle

Source: Business Insider

How regeneration works

Some animals can regenerate complex body functions with full functionality after amputation or injury. Invertebrates such as flatworms can reproduce the whole head from a tail and vice versa. Among vertebrates, fish can reproduce parts of the brain, eyes, kidneys, heart and fins. Frogs can regenerate limbs, tails, brains and eye tissues while in tadpole form. Salamanders can regenerate limbs, heart, tail, brain, eye tissue, kidneys, brain and spinal cord for their whole life.

Recent research on a variety of animals has shown that using stem cells can help regenerate body parts such as muscle, nerve and skin cells. By studying their organ regeneration cycle, scientists hope to find out how the human body can regenerate itself.

Recently, a team of US scientists led by Peter Reddien conducted a study on flatworms. The results showed that the flatworm body possessed pluripotent stem cells that played an important role in the regeneration process. In other animals such as frogs and salamanders, each different tissue has its own set of stem cells and only creates new cells corresponding to that tissue. In other words, skeletal muscle stem cells cannot form skin cells and vice versa.

In addition to stem cells, the body’s organ regeneration cycle is also based on the stimulation of differentiated cells that have stopped dividing, thereby replacing lost and damaged tissues. This has recently been verified in zebrafish, in which cardiac muscle cells divide themselves to replace lost heart tissue. Organ regeneration is also recorded in newborn mice and occurs at a slower rate as these animals grow up.

Organ regeneration cycle

Stem cell model of regeneration

Source: EuroStemcell

The potential of regenerating body organs with stem cells

Many common chronic conditions such as heart disease, liver cirrhosis, diabetes, and Parkinson’s disease occur when either our cells or the whole organ is damaged, hence impairing its function. The replacement of these cells is believed to provide an effective treatment of the aforementioned diseases. Based on this theory, regenerative medicine – which mainly focuses on stem cell therapy – has attracted the attention of researchers as well as the public.

Recently, scientists have successfully made a breakthrough in reprogramming adult cells and reverting them to the state of embryonic stem cells, which can differentiate into almost all types of cells. These include cells of less regenerative organs such as the heart.

Theoretically, stem cells can be utilized as an endless supply of cells. Scientists believe that products from stem cells can help restore the function of organs and aid in the treatment of various diseases. In addition, their role in the body’s organ regeneration cycle also gives rise to the use of stem cells for anti-aging and cosmetic purposes.

Read more: What diseases can stem cells cure?

GO.CARE’s regenerative medicine treatment

Studies on the body’s organ regeneration cycle have facilitated the development and perfection of stem cell therapies. Currently, this treatment is being performed at hundreds of hospitals and medical facilities around the world. Among them, several leading stem cell centers in Asia are GO.CARE’s partners. Over the years, many patients suffering from “incurable” chronic diseases have reached out to our partners and noted significant improvements thereafter.

Contact GO.CARE now for a FREE consultation about stem cell therapy. We will provide an answer to any question you may have and help you choose the most suitable treatment plan.

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Regeneration: what does it mean and how does it work? https://www.eurostemcell.org/regeneration-what-does-it-mean-and-how-does-it-work. Accessed on December 26, 2019.

How long it takes your body to regrow 19 types of cells and organs, from your skin to your skeleton. https://www.businessinsider.com/how-long-it-takes-the-body-to-grow-hair-nails-cells-2018-4. Accessed on December 26, 2019.

Regeneration. http://www.ahealth.com/content/education/ageless_lifestyle/media/regeneration.pdf. Accessed on December 26, 2019.

Stem cells could regenerate organs – but only if the body won’t reject them. http://theconversation.com/stem-cells-could-regenerate-organs-but-only-if-the-body-wont-reject-them-122017. Accessed on December 26, 2019.

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