A closer look at Stem cells and Aging - GO.CARE Blog

A closer look at Stem cells and Aging

Author: Jonathan Pham
Review Date: November 11, 2019 | Last Modified: November 29, 2019
A closer look at Stem cells and Aging

Nobody can avoid aging. As time goes by, wrinkles appear on our face at an intensifying rate. In addition, our muscle gradually weakens; our vision worsens, and we start catching diseases. For centuries, countless attempts have been made to slow down, or at least counteract the effects of aging on our bodies.

Over time, our cells gradually get damaged and die. As we grow older, the process of replacing dead cells become slower, which affects our bodies’ ability to sustain against diseases. Based on this, scientists have concluded that if fresh cells are introduced to the body, we will be able to slow down, or even reverse aging. This conclusion has given rise to the use of stem cell therapy for anti-aging.

What are stem cells?

Stem cells are fundamental cells that have the ability to create all other functional cells in the body. Essentially, they are the “building blocks” of every organism – as our body cells die due to injuries and illnesses, these cells evolve and adapt themselves to regenerate new ones.

Stem cells are found in many parts of our body, but they are mostly located in the blood, bone marrow, and adipose tissues. As the body gets damaged, these cells home to the injured areas and “differentiate” (transform) into the functional cells necessary for tissue regeneration.

The regenerating effects of stem cells have been drawing the interest of medical researchers, who believe that the use of these cells provides a reliable anti-aging method.

What happens to stem cells as we age?

According to a study at the Albert Einstein College of Medicine – New York in 2013, the part of the brain known as the hypothalamus is responsible for controlling aging. As stated by the leader of the research team – Dr. Dongsheng Cai, neural stem cells play a key role in the creation of brain nerve cells – this process is known as “neurogenesis”. As time goes by, the number of stem cells in the hypothalamus declines. At that point, aging symptoms start to surface.

In Dr. Cai’s study, experiments were conducted on a group of newborn mice. After about 10 months, the researchers started noticing a decrease in these animals’ number of hypothalamus stem cells. When the mice reached 2 years old, these stem cells were mostly lost. With a disruption in relevant neural stem cells, the aging process is further accelerated, and the death rate increases as well.

For humans, the same rule applies to us too. As we age, there will be an ongoing decrease in both the number and functionality of our stem cells. For example, the deterioration of functionality in hematopoietic stem cells – which are responsible for the creation of blood cells and cells in the immune system – is accountable for a steady drop in the number of white blood cells in the elderly. This, in turn, affects their ability to resist diseases and infections.

Aging-induced deterioration of stem cell functions and aging-associated diseases

How about stem cells in the brain?

Neural stem cells (NSCs) in the brain are responsible for the production of neurons such as glia to repopulate the brain cell pool. When we grow old, the regenerating capability of these stem cells gradually declines. According to a study at Stanford University, aged NSCs are characterized by a high number of broken proteins, which affect the functions of brain cells. The accumulation of these proteins is associated with the development of various degenerative diseases, including Alzheimer’s and Parkinson’s.

The researchers found out that by stimulating the clearance of the above-mentioned broken proteins, they would be able to restore the creation of nerve cells and active NSCs. This, in turn, would allow for improvements in the functions of the body’s neural cells.

Can the introduction of new stem cells stop aging?

To a certain extent, the effects of aging can be counteracted by refilling the pool of stem cells in the body. In Dr. Cai’s study, new stem cells were injected into the mice’s hypothalami. What happened next was a significant slowdown in these animals’ aging process. In addition, the researchers also noticed improvements in their muscular strength, cognitive functions, social behavior, etc.

Within recent years, additional research on stem cells has unveiled the potential of cellular therapies in treating aging. As one’s stem cell pool diminishes over the years, the introduction of fresh stem cells can make up for that. Upon being transplanted into the patient’s body, stem cells will stimulate the self-repair and rejuvenation of injured organs, hence reversing aging symptoms and delaying the effects of many diseases.

Unlike invasive procedures such as plastic & cosmetic surgery, stem cell-based anti-aging treatment does more than just changing one’s physical appearance. Thanks to their regenerative properties, these cells aid in restoring your energy levels and counteracting age-related damage to your body. As a result, not only does the patient can expect to look younger, but he/she should also experience better overall health.

The anti-aging potential of Stem cell treatment

Stem cell therapy allows for the repopulation of stem cells in your body. In addition, these cells also strengthen the existing cells and promote cell growth. These effects provide the basis for a non-invasive treatment method for aging.

At GO.CARE’s clinical partners, many patients have reported the following changes after receiving stem cell-based anti-aging treatment:

  • A more youthful outlook: better skin tone, fewer wrinkles and age spots.
  • Improved levels of energy, less fatigue.
  • Reduced muscle stiffness and pain.
  • Better mood and libido.
  • Hair growth and color changes.

Among the different types of cells in use now, Mesenchymal stem cells (MSCs) are the most prominent and have been widely used in the treatment of various chronic conditions. In addition, these cells also play a key part in the regeneration of many body parts, including the skin, bone, and muscle.

Where can I get stem cell-based Anti-aging treatment?

If you are interested in treating aging with stem cells, look no further. GO.CARE provides you with access to the services of the best stem cell centers in Southeast Asia. Our partners have treated hundreds of patients, most of whom have reported significant improvements in their life quality afterward.

Contact GO.CARE now to get a FREE consultation and book a trip to our leading stem cell clinics. We are more than happy to help you get the youthful outlook and well-being that you deserve!

You GO and we CARE!

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Effect of aging on stem cells. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316899/. Accessed on November 11, 2019.

Can stem cells help with aging? https://www.nationalstemcellcenters.com/2018/06/15/can-stem-cells-help-with-aging/. Accessed on November 11, 2019.

Could stem cells reverse the aging process? https://www.medicalnewstoday.com/articles/318639.php. Accessed on November 11, 2019.

Stem Cells and Aging – What Happens When Our Stem Cells Get Old and Tired?. https://www.closerlookatstemcells.org/2018/10/01/stem-cells-and-aging-what-happens-when-our-stem-cells-get-old-and-tired/. Accessed on November 11, 2019.

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